April 12-16th, 2027
5th RESOLUTION DAYS
The resolution of inflammation,
new avenues and opportunities for innovative therapeutics?
Eden Roc Hotel
Costa Brava, SPAIN
scientific and organizing committee
Annabel Fernandez Valledor (ES), Maria Rosa Sarrias Fornes (ES),
Amiram Ariel (IS), Jesmond Dalli (UK) & Sylvain Perruche (FR)
a join meeting edition with:
April 8-10th, 2025
Frankfurt - GERMANY
at The Crowne Plaza Frankfurt Congress Hotel
4th RESOLUTION DAYS
Organizers:
Andreas Weigert, Manuela Diehl, Susanne Behlke & Sylvain Perruche
with the contribution of the
iiSIAR Study Group, EFIS, EJI
program
The resolution of inflammation,
new avenues and opportunities for innovative therapeutics?
MONDAY, APRIL 7th
Lobby
18:00–19:00, Arrival and Registration
TUESDAY, APRIL 8th
Room Frankfurt 2
08:30, Welcome Address
08:45–14:45
New mediators and mechanisms
Room Frankfurt 2
Chairs: Stephanie Dakin and Andreas Weigert
Dipak Panigrahy Beth Israel Deaconess Medical Center, US
“SPMs & the Resolution of Inflammation in Cancer”
Stefan Offermanns Max Planck Institute for Heart and Lung Research Bad Nauheim, DE
"How are cellular SPM effects mediated?"
Selected talk from abstracts:
A. Weigert Goethe-University Frankfurt, DE
Abstract #26 “Interleukin-38 at the crossroads of auto-inflammation and anti-tumor immunity”
10:45, Coffee break
Gallery and Lobby
Kiavash Movahedi University of Brussels, BE
"The fate of brain macrophages following disease resolution"
Selected short talk from abstracts:
T. Montero-Melendez Queen Mary University of London, UK
Abstract #36 “Therapeutic senescence using melanocortins to induce inflammation resolution”
12:30, Lunch
hotel restaurant
14:00
Jesmond Dalli Queen Mary University of London, UK
"Unlocking SPM Pathways: Bridging Inflammation Resolution and Tissue Repair to Human Health"
14:45–18:45
Resolution and ageing
Room Frankfurt 2
Chairs: Susanne Behlke and Jesmond Dalli
Kodi Ravichandran Washington University School of Medicines, USA
"Efferocytosis by phagocytes – challenges to having a good meal"
Oliver Werz Friedrich Schiller University Jena, DE
“Regulation of lipoxygenases in innate immune cells to promote inflammation resolution”
3 Selected short talks from abstracts:
L. Soong University Of Texas Medical Branch, USA
Abstract #16 “Unique Cellular and Humoral Immunity Profiles in Preclinical Models of Self-limiting versus Severe Scrub Typhus”
G. Merheb Université Paris Cité FR
Abstract #75 “Effects of Omega-3 and SPM on Human Coronary Vascular Tone Induced by Neurotransmitters”
C. Crispens Goethe University , DE
Abstract #18 “Impact of Senescence on Inflammatory Dynamics in Acute Lung Injury: Age and Sex as Key Elements”
17:00, Coffee break
Gallery and Lobby
Angela Goncalves DKFZ German Cancer Research Center, DE
"Inflammation in the female reproductive tract: what is left after 'scarless' cycling?"
3 Selected talks from abstracts:
T. Burstyn-Cohen The Hebrew University, IS
Abstract #46 “Microglia Development, Phagocytosis and Inflammation are Regulated by PROS1”
C. Gerner University of Vienna, AT
Abstract #53 “Investigating molecular mechanisms of the pro-resolving effects of antioxidant supplementation and extracorporeal photopheresis”
E. Avci Max Planck Institute, DE
19:00, Dinner
hotel restaurant
19:00-22:00, Poster Session I
Room Frankfurt 1
WEDNESDAY, APRIL 9th
08:30–14:55
Resolution and metabolism
Room Frankfurt 2
Chairs: Tal Burstyn-Cohen and Kodi Ravichandran
Ingrid Fleming Goethe-Universität Frankfurt, DE
"Targeting TGF-b signaling by deleting SMOC1 prevents the resolution of inflammation"
Ulrich Matt Universitätsklinikum Gießen und Marburg, DE
"Cell type specific efferocytosis instructs macrophage function during resolution of inflammation"
10:30, Coffee break
Gallery and Lobby
2 Selected talks from abstracts:
D. Steinhilber Goethe University Frankfurt, DE
Abstract #10 “Canonical and noncanonical functions of 5-lipoxygenase in the onset and resolution of inflammation”
M. Subramanian Queen Mary University of London, UK
Abstract #12 “Macrophages are critical for clearance of neutrophil extracellular traps in tissues”
2 Selected short talks from abstracts:
P. M. Jordan Friedrich Schiller University Jena, DE
Abstract #7 “Screening of anti-inflammatory natural products uncovers bioactive candidates for promoting endogenous inflammation resolution signals”
H. Badji Université Paris Cité, FR
Abstract #85 “Unlocking the Potential of Specialized Pro-Resolving Mediators in Pulmonary Hypertension: A New Approach to Vascular Tone Regulation”
12:25, Lunch
hotel restaurant
13:40
Sponsored talk: Bruno Fink Noxygen Science Transfer & Diagnostics GmbH
“A plant-based dietary supplement exhibits significant effects on markers of oxidative stress, inflammation and immune response in subjects recovering from respiratory viral infection. A randomized, double-blind clinical study using Vitamin C as 5 a positive control”
14:55
Johan Garaude Université de Bordeaux, FR
"Microbial viability drives immunometabolic responses of macrophages"
15:40-19:05
Resolution and regeneration
Room Frankfurt 2
Chairs: Astrid Stephanie Kahnt and Sylvain Perruche
Mikael Simons Technical University Munich, DE
“Role of the Innate Immune System in Myelin Repair within the Central Nervous System”
Pedro Melgar-Lesmes University of Barcelona, ES
"The paradigm of macrophages on liver fibrosis resolution and regeneration"
17:10, Coffee break
Gallery and Lobby
Sven Reischauer Justus Liebig University Gießen, DE
2 Selected talks from abstracts:
S. A. Rizo University of Montreal, QC
Abstract #68 “Interferon-beta drives the resolution of neutrophil-mediated pulmonary inflammation by switching between LTB4 and specialized pro-resolving lipid mediator biosynthesis”
N. Prevete University of Naples Federico II, IT
Abstract #70 “Formyl peptide receptor 1 signalling strength orchestrates the switch from inflammation to resolution in colon cancer cells”
3 Selected short talks from abstracts:
J. Chen Queen Mary University of London, UK
Abstract #47 “Targeting Fpr1/Fpr2 Signaling to Mitigate Secondary Organ Damage in Inflammatory Arthritis”
M. Cattaneo Goethe University Hospital, DE
Abstract #67 “Combination therapy of autoimmune liver diseases by administration of an anti-CD3 antibody and a CXCR3 antagonist”
J. Lückgen BioMed X Institute, DE
Abstract #89 “Spatially-resolved functional maps of synovial macrophages and structural cells in remission and inflammatory arthritis”
19:30, Dinner
hotel restaurant
19:30-22:00, Poster Session II
Room Frankfurt 1
THURSDAY, APRIL 10th
08:30-11:55
Translational resolution
Room Frankfurt 2
Chairs: Susanne Behlke and Johan Garaude
Andreas Ramming University Clinic Erlangen, DE
“Active Role of Fibroblasts during Onset and Resolution of Arthritis”
Stephanie G Dakin University of Oxford, GB
"Primed to resolve: The shoulder capsule reveals a cellular basis for resolving inflammatory fibrosis"
10:00, Coffee break
Gallery and Lobby
2 Selected talks from abstracts:
S. Gupta University of Rostock, DE
Abstract #80 “Comparative Analysis of Multicomponent Tr14 and Single-Component Diclofenac in Modulating the Neutrophil-Macrophage Axis for Inflammation Resolution”
N. Ben Jashar University of Haifa, IS
Abstract #17 “The BiST of Burden: Harnessing biased STING agonists to enhance the resolution of inflammation and limit tissue fibrosis”
2 Selected short talks from abstracts:
M. Denkewitz University Hospital, DE
Abstract #40 “Coronaviruses impair resolution phase in monocytes via aberrant interferon signalling”
A. Chakravarty University of Zurich, DE
Abstract #84 “Minor Association of Oxylipins with Adolescent Depression: A Case-Control Study”
12:00, Advancing Resolution’s Network
Susanne Behlke MED’INN’PHARMA, FR
12:15, Lunch
hotel restaurant
13:30-17:00
iiSIAR Study Group Session
Innate immunity in sterile inflammation, autoimmunity, and their resolution
Room Frankfurt 2
13:30, KEYNOTE
Chairs: Zsuzsa Szondy and Amiram Ariel
Nicolas Manel Institut Curie, FR
"Activation of nuclear cGAS by self DNA"
14:15-16:10, SESSION 1
3 selected talks from Forum:
R. Bernhard CNRS, FR
Abstract #22 “Chronic ozone induced Th2 response mimicking COPD”
A. F. Valledor University of Barcelona, SP
Abstract #78 “Selective cooperation of Liver X Receptors and Inflammation-Induced C/EBPβ impacts CD38 expression”
A. Lučiūnaitė Vilnius University, LTU
Abstract #34 “Investigation of inflammasome activation by phagocytosed particles”
15:15, Break
Gallery and Lobby
15:25, KEYNOTE
Chairs: Annabel Valledor and Maciej Kurpisz
Anne Dejean Institut Toulousain des Maladies Infectieuses et Inflammatoires, FR
"Eomes, a new actor in shaping Tregs identity and plasticity"
16:10-17:10 SESSION 2
3 selected talks from Forum:
Z. Szondy University of Debrecen, HU
Abstract #61 “INVOLVEMENT OF ADENOSINE RECEPTORS IN THE REGULATION OF SKELETAL MUSCLE REGENERATION IN MICE”
T. Bruurmijn Citryll B.V., NL
Abstract #44 “Anti-citrullinated histone antibody CIT-013 reduces inflammation by targeting NETs, highlighting its therapeutic potential in Rheumatoid Arthritis.”
C. Testini Uppsala University, SE
Abstract #91 “Lyve1+ macrophages contribute to vascular density and perfusion important for tissue normalization during healing of ischemic injuries”
17:15, closing remarks
17:30, end
FRIDAY, APRIL 11th
Departure
