3rd EDITION

April 26-29th, 2023

Besançon - FRANCE

program
 
The resolution of inflammation:
opportunities for innovative therapeutics ?

 

WENESDAY, APRIL 26th

Lobby

18:00–20:00, Arrival and Registration

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Victor Hugo room

18:00–20:00, Poster Setup 
19:00–22:00, Opening poster Session
19:30–22:00, Buffet

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THURSDAY, APRIL 27th

Frères Lumière room

08:00–09:00, Welcome and Keynote Address

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Charles Serhan Harvard Medical School, USA

"Human Leukocytes biosynthesize novel Resolvins that link Resolution of Inflammation, Tissue Regeneration and Wound Healing”

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PART1:

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          PART2:

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09:00–13:00, Biological and cellular mechanisms of resolution I

Chairs: Amiram Ariel & Ariella Glasner

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Jesmond Dalli Queen Mary University of London, UK

"Insights into the biology of specialized pro-resolving mediators and their receptors in phagocytes"

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Selected TALK (selected from abstracts)

- Bruce D. Levy, Harvard Med School, USA: Resolvin D2 Regulates Eosinophil Phenotype and Function During Allergic Lung Inflammation
 

SHORT TALKS (selected from abstracts)

- Gaelle Merheb, LVTS, FR: DHA, RvD1, RvD5, and/or MaR1 reduce human arteries contractions induced by PGE2
- Hildur Arnardottir, Karolinska U, SWE: Resolvin D3 attenuates angiotensin-II-induced valve thickening and dysfunction in apolipoprotein E-deficient mice and promotes macrophage reprogramming

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Amiram Ariel, Haifa U, ISR: Future activities in the field of Resolution of Inflammation

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Coffee break (Victor Hugo room)

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Detlef Schuppan Institute of Translational Immunology, Mainz, DE

"Targeted therapies to resolve liver fibrosis and NASH"

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Sanja Arandjelovic U of Virginia, USA

“Efferocytosis machinery proteins in inflammatory arthritis”

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SHORT TALKS (selected from abstracts)

- Javier Perez Hernandez, Cochin Institute, FR: Altered lipid mediator profile in type 1 diabetes : defective resolution of inflammation in pancreatic islets ?
- Purbasha Bhattacharya, CSIR Institute, IND: Efferocyte-derived extracellular vesicles promote inflammation resolution
- Szondy Zsuzsanna, Debrecen U, HUN: Involvement of efferocytosis in the regulation of M2-like reparative macrophage formation during regenerative inflammation

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13:00 lunch & Visits of the City or of City's Citadelle

 

Victor Hugo room

13:00–22:00, Poster Viewing

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Frères Lumière room

16:30–20:00, Clinical implication of resolution impairment

Chairs: Sylvaine You & Andreas Weigert

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Adriano G Rossi University of Edinburgh, UK

“Novel pharmacological strategies to enhance granulocyte apoptosis and efferocytosis to promote inflammation resolution”

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Catherine Godson University College Dublin, IE

"Dubloxins attenuate inflammation and fibrosis"

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SHORT TALKS (selected from abstracts)

- Oliver Werz, Friedrich Schiller U, DEU: Glucocorticoids regulate pro-resolving lipid mediator biosynthesis via antipodal modulation of 15-lipoxygenase isoforms affecting inflammation resolution
- Toru Miyazaki, AIM Medecine Institute, JPN: Facilitation of disease repair through phagocytic removal of different inflammatory elements by AIM/CD5L

 

Break & Refreshments (Victor Hugo room)

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Gabrielle Fredman Albany Medical College, USA

"Inflammation-resolution in atherosclerosis and aging"

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Markus Hoffmann Universität zu Lübeck, DE

"Mesenchymal cell control of inflammatory tissue priming"

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Elizabeth Redente National Jewish Health, USA

"Reducing Fibroblast Persistence in Pulmonary Fibrosis as a Mechanism of Resolution"

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Victor Hugo room

20:00, Social Hours to "meet the speaker" & Buffet

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20:00–22:00, Second Poster Session

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FRIDAY, APRIL 28th

Frères Lumière room

09:00–13:00, Biological and cellular mechanisms of resolution II

Chairs: Janos Filep & Claudia Jakubzick

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David Lagares Harvard Medical School, USA

“Fibrosis Resolution: Mechanisms and Therapeutic Opportunities”

 

Oliver Soehnlein University of Münster, DE

"Neutrophils in chronic inflammation – from physiology to intervention"

 

SHORT TALKS (selected from abstracts)

- Blandine Baffert, RIGHT institute, FR: Targeting macrophages to resolve fibrosis in a bleomycin-induced model
- Salma Rizo Téllez, Research Center, CA-QC: An interferon-B-FPR2/ALX-centered axis promotes the resolution of pulmonary inflammation

 

Coffee break (Victor Hugo room)

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Claudia Jakubzick Dartmouth Geisel School of Medicine, NH

"The Role of moDCs and Interstitial Macrophages in the Lung"

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Andreas Weigert Institute of Biochemistry I Goethe-University Frankfurt, DE

“Interfering with apoptotic cell-derived signals in cancer”

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Selected TALK (selected from abstracts)

- Thomas E. Van Dyke (The Forsyth Institute, USA): Applied Resolution Pharmacology in Periodontal Disease Treatment and Periodontal Regeneration
 

SHORT TALKS (selected from abstracts)

- Mirza S. Baig, IITI, IND: The dynamic role of toll-interleukin 1 receptor (TIR) domain-containing adaptor protein (TIRAP) in the progression of inflammatory response
- Roi Gazit, Ben-Gurion U, ISR: Hematopoietic Stem Cells suffer from Chronic Salmonella Infection -- and may Recover 

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13:00 lunch & Visits of the City or of City's Citadelle

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Frères Lumière room

16:30–20:00, Resolution pharmacology

Chairs: Sylvain Perruche & Susanne Behlke

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Shuang Liang U of Texas Southwestern Medical Center, USA

"Efferocytosis in Fatty Liver and NASH"

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SHORT TALKS (selected from abstracts)

- Ariella Glasner, TIIT, ISR: Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs novel combination cancer therapy strategies
- Dipak Panigrahy, Harvard Med School, USA: Pro-resolving lipid mediators prevent cancer cachexia

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Dror Mevorach The Hebrew University of Jerusalem, IS

"Clearance of apoptotic cells in cancer: Resolution of inflammation or macrophage reprogramming?"

  

Break & Refreshments (Victor Hugo room)

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Vanessa Gauttier OSE Immunotherapeutics, FR

"Anti-ChemR23 agonist pro-Resolutive mAbs"

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SHORT TALKS (selected from abstracts)

- Nofar Ben Jashar, Haifa U, ISR: The BiST of Burden: Harnessing biased STING agonists to enhance the resolution of inflammation and limit tissue fibrosis
- Sylvain Perruche, MED'INN'PHARMA, FR: Therapeutic potential of the secretome of resolution phase macrophages

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Mauro Perretti Queen Mary University of London, UK

"Resolution Pharmacology: a new way to control chronic diseases"

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Victor Hugo room

20:00–23:00, Gala Diner                                   

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SATURDAY, APRIL 29th

Departure