April, 2027
5th RESOLUTION DAYS
The resolution of inflammation,
new avenues and opportunities for innovative therapeutics?
Eden Roc Hotel
Costa Brava, SPAIN
scientific and organizing committee
Annabel Fernandez Valledor (ES), Maria Rosa Sarrias Fornes (ES),
Amiram Ariel (IS), Jesmond Dalli (UK) & Sylvain Perruche (FR)
1st EDITION
April 4-6th, 2018
Besançon - FRANCE
program
WENESDAY, APRIL 4
16:00–20:00 Lobby Arrival and Registration
19:30–21:00 Victor Hugo room Welcome dinner
THURSDAY, APRIL 5
07:00–08:00 Breakfast room Breakfast
08:00–09:00 Frères Lumière room Welcome and Keynote Address
Sylvain Perruche, INSERM UMR1098, EFS BFC U of BFC, FR
Dror Mevorach, Hadassah-Hebrew University Medical Center, Jerusalem, ISR
Resolution of inflammation by macrophages and dendritic cells
09:00–12:00 Frères Lumière room Mechanisms of efferocytosis
CHAIRMAN: Philippe Saas, INSERM UMR1098, EFS BFC, U of BFC, FR
Sanja Arandjelovic, Center for Cell Clearance, University of Virginia, USA
Apoptotic cell engulfment machinery in arthritis
Toby Lawrence, INSERM U1104, Marseille, FR
NF-kappaB signalling in the resolution of inflammation and immune homeostasis
Luis E Muñoz, U of Erlangen, DE
The immunological meaning of necrosis
Coffee Break
Philippe Saas, INSERM UMR1098, EFS BFC, U of BFC, FR
Modulation of immune responses by apoptotic cell infusion
Short Talks:
Philippe Frachet, Institut de Biologie Structurale, U of Grenoble, FR
Soluble calreticulin released from apoptotic cells modulates the macrophage polarization
Adam Ceroi, VIB-UGent Inflammation Research Center, BE
Extracellular vesicles, engulfment, and airway inflammation
David Masson, LNC UMR1231, U of BFC, Dijon, FR
Impact of Liver X receptors on efferocytosis: New targets and additional mechanisms
On own for lunch
11:30–13:00 Victor Hugo room Poster Setup
13:00–22:00 Victor Hugo room Poster Viewing
16:30–17:00 Frères Lumière room Coffee Available
17:00–20:00 Frères Lumière room Pro-resolutive factors in Resolution
CHAIRMAN: Charles N. Serhan
Charles N. Serhan, Harvard Medical School, USA
Resolvins and Specialized Pro-Resolving Mediators in Inflammation and Infection
Dipak Panigrahy, William Harvey Research Institute - Queen Mary U of London, UK
Resolvins suppress tumor growth and enhance cancer therapy
Derek Gilroy, Centre for Clinical Pharmacology, U College London, UK
Impact of age on pro-resolution pathways in humans
Wanjun Chen, Mucosal Immunology section, NIDCR, NIH, USA
Apoptotic cell-mediated immunoregulation: the roles of TGF-beta and Tregs
Short Talks:
Daniela Fussbroich, University of Applied Sciences, Fulda, DE
A specific combined long-chain polyunsaturated fatty acid supplementation exhibits pro-resolving effects and restores disease-altered fatty acid profiles in asthmatic mice
Aparna Mahajan, Friedrich Alexander University, Erlangen, DE
Prolonged eye closure induced inflammation resolved by proteolytically active NETs in eyerheum
Valérie Urbach, INSERM U1151, U Paris Descartes, Paris, FR
Resolvin D1 normalizes epithelial ion transport and resolution of inflammation in cystic fibrosis airways
20:00 Victor Hugo room Social Hours with Dinner
20:00–22:00 Victor Hugo room Poster Session
* chairman
Friday, April 6
07:00–08:00 Breakfast room Breakfast
08:00–12:00 Frères Lumière room Cell subsets in Resolution
CHAIRMAN: David Masson
Adriano Rossi, Center for Inflammation Research, Queen's Medical Research Institute, U of Edinburgh, UK
Therapeutic Strategies to Enhance the Resolution of Inflammation to Promote Tissue Repair and Regeneration
Héléna Paidassi, Centre International de Recherche en Infectiologie, U de Lyon, FR
Sensing your way out of trouble : what shapes dendritic cells into critical gatekeepers of immune homeostasis
Amiram Ariel, Faculty of Natural Sciences, U of Haifa, ISR
IFN-β, a novel effector in resolving inflammation
Coffee Break
Véronique Witko-Sarsat, U1016, Institut Cochin, Paris, FR
Proliferating Cell Nuclear Antigen in neutrophils: a potential target to modulate inflammation
Short Talks:
Darja Andreev, Friedrich Alexander University, Erlangen, DE
Eosinophils induce resolution of inflammatory arthritis and protection against bone loss
Alban Gaultier, University of Virginia, Charlottesville, USA
Sigma-1 Receptor controls IRE1 activity to inhibit Endoplasmic Reticulum driven inflammation
Markus H Hoffmann, Friedrich Alexander University, Erlangen, DE
Neutrophil- but not eosinophil-derived aggregated extracellular traps resolve inflammation by proteolysis of cytokines and chemokines
On own for lunch
13:00–2300 Victor Hugo room Poster Viewing
16:30–17:00 Frères Lumière room Coffee available
17:00–20:00 Frères Lumière room Resolution-inspired therapeutic approaches
CHAIRMAN Dror Mevorach
Hendrik Ankersmit, Division of Thoracic Surgery, Medical U of Vienna / Aposcience AG, AT
Apoptotic PBMC secretome as therapeutic Agent: from science to regulatory to clinical trial
José Cohen, Unité mixte de recherche S955, U of Paris Est Créteil, FR
TNFR2: The new Treg switch
Sylvain Perruche, INSERM UMR1098, EFS BFC, U of BFC, FR
Efferocytosis factors as a therapeutic biological drug to terminate inflammation
Daniele Noel, Institute of Regenerative Medicine and Biotherapies, INSERM, U of Montpellier, FR
Mesenchymal stem cells in osteoarthritis: lessons from clinical trials and perspectives towards an acellular therapy
Short Talks:
Sylvaine You, Institut Cochin, Paris, FR
Resetting self-tolerance in autoimmune diabetes by pro-resolving mediators derived from apoptotic cell efferocytosis
Dror Mevorach, Hadassah-Hebrew, U Medical Center, Jerusalem, ISR
Cell therapy using apoptotic cells
Charlène Trilleaud, University of Nantes, Nantes, FR
Triggering the resolution pathway with an agonistic anti-ChemR23 antibody ameliorates recovery in preclinical colitis models
20:00–23:00 Victor Hugo room Gala Dinner
Saturday, April 7
10:00 Departure
