April 8-10th, 2025
Frankfurt - GERMANY
at The Crowne Plaza Frankfurt Congress Hotel
4th RESOLUTION DAYS
The resolution of
inflammation,
opportunities for
innovative
therapeutics?
Organizers:
Andreas Weigert, Manuela Dieh, Susanne Behlke & Sylvain Perruche
1st EDITION
April 4-6th, 2018
Besançon - FRANCE
program
WENESDAY, APRIL 4
16:00–20:00 Lobby Arrival and Registration
19:30–21:00 Victor Hugo room Welcome dinner
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THURSDAY, APRIL 5
07:00–08:00 Breakfast room Breakfast
08:00–09:00 Frères Lumière room Welcome and Keynote Address
Sylvain Perruche, INSERM UMR1098, EFS BFC U of BFC, FR
Dror Mevorach, Hadassah-Hebrew University Medical Center, Jerusalem, ISR
Resolution of inflammation by macrophages and dendritic cells
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09:00–12:00 Frères Lumière room Mechanisms of efferocytosis
CHAIRMAN: Philippe Saas, INSERM UMR1098, EFS BFC, U of BFC, FR
Sanja Arandjelovic, Center for Cell Clearance, University of Virginia, USA
Apoptotic cell engulfment machinery in arthritis
Toby Lawrence, INSERM U1104, Marseille, FR
NF-kappaB signalling in the resolution of inflammation and immune homeostasis
Luis E Muñoz, U of Erlangen, DE
The immunological meaning of necrosis
Coffee Break
Philippe Saas, INSERM UMR1098, EFS BFC, U of BFC, FR
Modulation of immune responses by apoptotic cell infusion
Short Talks:
Philippe Frachet, Institut de Biologie Structurale, U of Grenoble, FR
Soluble calreticulin released from apoptotic cells modulates the macrophage polarization
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Adam Ceroi, VIB-UGent Inflammation Research Center, BE
Extracellular vesicles, engulfment, and airway inflammation
David Masson, LNC UMR1231, U of BFC, Dijon, FR
Impact of Liver X receptors on efferocytosis: New targets and additional mechanisms
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On own for lunch
11:30–13:00 Victor Hugo room Poster Setup
13:00–22:00 Victor Hugo room Poster Viewing
16:30–17:00 Frères Lumière room Coffee Available
17:00–20:00 Frères Lumière room Pro-resolutive factors in Resolution
CHAIRMAN: Charles N. Serhan
Charles N. Serhan, Harvard Medical School, USA
Resolvins and Specialized Pro-Resolving Mediators in Inflammation and Infection
Dipak Panigrahy, William Harvey Research Institute - Queen Mary U of London, UK
Resolvins suppress tumor growth and enhance cancer therapy
Derek Gilroy, Centre for Clinical Pharmacology, U College London, UK
Impact of age on pro-resolution pathways in humans
Wanjun Chen, Mucosal Immunology section, NIDCR, NIH, USA
Apoptotic cell-mediated immunoregulation: the roles of TGF-beta and Tregs
Short Talks:
Daniela Fussbroich, University of Applied Sciences, Fulda, DE
A specific combined long-chain polyunsaturated fatty acid supplementation exhibits pro-resolving effects and restores disease-altered fatty acid profiles in asthmatic mice
Aparna Mahajan, Friedrich Alexander University, Erlangen, DE
Prolonged eye closure induced inflammation resolved by proteolytically active NETs in eyerheum
Valérie Urbach, INSERM U1151, U Paris Descartes, Paris, FR
Resolvin D1 normalizes epithelial ion transport and resolution of inflammation in cystic fibrosis airways
20:00 Victor Hugo room Social Hours with Dinner
20:00–22:00 Victor Hugo room Poster Session
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* chairman
Friday, April 6
07:00–08:00 Breakfast room Breakfast
08:00–12:00 Frères Lumière room Cell subsets in Resolution
CHAIRMAN: David Masson
Adriano Rossi, Center for Inflammation Research, Queen's Medical Research Institute, U of Edinburgh, UK
Therapeutic Strategies to Enhance the Resolution of Inflammation to Promote Tissue Repair and Regeneration
Héléna Paidassi, Centre International de Recherche en Infectiologie, U de Lyon, FR
Sensing your way out of trouble : what shapes dendritic cells into critical gatekeepers of immune homeostasis
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Amiram Ariel, Faculty of Natural Sciences, U of Haifa, ISR
IFN-β, a novel effector in resolving inflammation
Coffee Break
Véronique Witko-Sarsat, U1016, Institut Cochin, Paris, FR
Proliferating Cell Nuclear Antigen in neutrophils: a potential target to modulate inflammation
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Short Talks:
Darja Andreev, Friedrich Alexander University, Erlangen, DE
Eosinophils induce resolution of inflammatory arthritis and protection against bone loss
Alban Gaultier, University of Virginia, Charlottesville, USA
Sigma-1 Receptor controls IRE1 activity to inhibit Endoplasmic Reticulum driven inflammation
Markus H Hoffmann, Friedrich Alexander University, Erlangen, DE
Neutrophil- but not eosinophil-derived aggregated extracellular traps resolve inflammation by proteolysis of cytokines and chemokines
On own for lunch
13:00–2300 Victor Hugo room Poster Viewing
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16:30–17:00 Frères Lumière room Coffee available
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17:00–20:00 Frères Lumière room Resolution-inspired therapeutic approaches
CHAIRMAN Dror Mevorach
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Hendrik Ankersmit, Division of Thoracic Surgery, Medical U of Vienna / Aposcience AG, AT
Apoptotic PBMC secretome as therapeutic Agent: from science to regulatory to clinical trial
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José Cohen, Unité mixte de recherche S955, U of Paris Est Créteil, FR
TNFR2: The new Treg switch
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Sylvain Perruche, INSERM UMR1098, EFS BFC, U of BFC, FR
Efferocytosis factors as a therapeutic biological drug to terminate inflammation
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Daniele Noel, Institute of Regenerative Medicine and Biotherapies, INSERM, U of Montpellier, FR
Mesenchymal stem cells in osteoarthritis: lessons from clinical trials and perspectives towards an acellular therapy
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Short Talks:
Sylvaine You, Institut Cochin, Paris, FR
Resetting self-tolerance in autoimmune diabetes by pro-resolving mediators derived from apoptotic cell efferocytosis
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Dror Mevorach, Hadassah-Hebrew, U Medical Center, Jerusalem, ISR
Cell therapy using apoptotic cells
Charlène Trilleaud, University of Nantes, Nantes, FR
Triggering the resolution pathway with an agonistic anti-ChemR23 antibody ameliorates recovery in preclinical colitis models
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20:00–23:00 Victor Hugo room Gala Dinner
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Saturday, April 7
10:00 Departure